Multi Objective Optimization Approach for Biomedical Stent using Parametric Optimization

Stent deployment process and its long-term usage requires to meet multiple objectives like final stent diameters for cardiovascular disease treatments, and minimalistic plastic strain during the deployment to meet the fatigue life. Achieving an exact dilation diameter and maintaining minimal plastic strain values are mainly based on stent geometric design, cross section, material, amount of crimping and expansion diameter. This paper presents an effective stent finite element (FE) modelling and parametric optimization method using DEP MeshWorks stent rolling and parametric tools, LS-DYNA and LS-OPT optimization tools. Controllable design and deployment process parameters are considered for optimum random sampling using a Design of Experiments (DOE) approach, and using a parametric tool, designs are generated, on which analysis and optimization is performed using LS-DYNA explicit solver. The result is an optimum design solution which meets the required diameter criteria, without exceeding the minimal plastic strain limit, and within the foreshortening and flexibility limits.